So how exactly has it always been so popular? Phentermine and phentermine hydrochloride gained popularity as being short-term cures to obesity. In the twentieth century, phentermine was one of the very few weight loss drugs available in the market. The price of phentermine has always been low when compared to its competitors, some of them that have way fewer side effects. Other diet drugs such as Xenical and Meridia are priced significantly higher than phentermine.
There have been numerous allegations over the last fifty years that physicians have directly and indirectly benefited from prescribing phentermine and its various combinations to money conscious patients.
However, this is nothing out of the ordinary when it comes to prescription drugs as pharmaceutical companies have time and again been accused of these practices. Phentermine's popularity is also historically linked with the popularity of fenfluramine. When fenfluramine was developed in the s, the drug was expected to become a market leader in the segment.
However, this was vastly different from the ground reality. Most patients who consumed fenfluramine complained of effects such as anxiety and nausea on a large scale basis. American Home Products manufactured the drug under the name Pondimin, but the market sales were extremely poor and it never caught on as a suitable alternative to regular exercise and dieting.
In , researchers at the University of Rochestor stated that the combination of phentermine and fenfluramine was incredibly effective as an obesity combatant.
The research team, led by Dr. Micheal Weintraub, believed that this combination did not cause the same irritating side effects that other diet drugs did. This led to a huge surge in the popularity and sales of phentermine. Fen-Phen was highly successful in the market as there were cases in which patients were able to drop as much as 30 pounds in a couple of months.
As the popularity of Fen-Phen soared, American Home Products was worried as the patent the company held for Pondimin was about to expire. The company was against the idea of its competitors getting their hands on fenfluramine and the burgeoning profits of Fen-Phen. American Home Products had to find a solution to this problem before their market share dipped. This problem was solved by the introduction of Redux to the market.
American Home Products and its subsidiaries developed a brand new version of fenfluramine, which happened to be known as dexfenfluramine. The FDA was particularly wary about this new weight loss drug, but it approved the drug in after intensive debates about its potentially harmful effects. The introduction of Dexfen-Phen reinvigorated the market, and it was thought to be even better than Fen-Phen when it came to fighting obesity.
Just like the fenfluramine and phentermine combine, Dexfen-Phen was not intensively tested for safety. The company's focus at this time was to ensure that the FDA would approve its new product before the patent on fenfluramine ran out. As such, it was not highly preoccupied with the adverse effects of dexfenfluramine on the people who consumed it. As the sales of Dexfen-Phen were rising in , multiple reports of its adverse effects and its links to coronary heart disease surfaced and a few patients consuming the medication ended up dead, including some patients who had a history of clean health.
The FDA could no longer sit idle and it banned the commercial distribution of dexfenfluramine and fenfluramine. What are the side effects of phentermine? Phentermine has multiple side effects that have come to the fore in various ways over the years.
Phentermine's contentious history has time and again led to numerous experts to call for its removal from the market, but the drug has managed to stay in distribution thanks to a number of factors. Some of the side effects of phentermine include severe chest pain, decreased energy levels, dizziness and fainting, irregular and rapid heartbeat, swelling and trembling of the feet, thought impairment, headaches, and numbness of the arms and legs.
The effects also include restlessness, euphoria, hypertension, diarrhea, dry mouth, facial oedema, impotence, urticaria, and arrhythmia. Phentermine has been known to have various gastrointestinal effects on the body. This primarily includes vomiting and cramps.
Acute transient ischaemic colitis has also been linked to regular intake of phentermine. The dermatological effects of the drug include pale skin and drying of the mucous membrane.
The drug also has notable genitourinary effects. Acute urinary retention is a common symptom. Renal ischemia is possible, and renal failure can also occur in tandem with dehydration and rhabdomolysis. Phentermine is also known to have severe effects on the body's endocrine system. Patients who have been consuming phentermine for at least eight weeks have been known to report significant changes in libido in addition to instances of decreased sexual interest and impotence.
Geriatric patients have also been known to be more sensitive to phentermine. Geriatric patients should be prescribed very small amounts of phentermine to begin with. This is because their cardiovascular, renal, endocrine, hepatic, and other functions are likely to be much lower than that of younger adults.
The kidneys are known to excrete substantial amounts of phentermine and this is more likely to lead to toxic reactions in geriatric patients, as they are likely to have weaker renal functions. There are numerous medications that may interact with phentermine and produce harmful side effects. Dexfenfluramine and fenfluramine are primary examples of this problem, having played a great role in causing heart diseases.
Substances such as phenelzine and furazolidone are contraindicated because they may lead to elevated blood pressure levels, decreased heart rate, elevated body temperature levels, and even severe lung problems. Potential to cause heart disease and pulmonary hypertension Cardiovascular diseases associated with phentermine have been suspected since the s. Various causes of palpitations, ischemic events, and tachycardia have been reported.
Although a large majority of these cases have been reported by people taking the Fen-Phen or Dexfen-Phen combo, rare cases of patients who have only taken phentermine have reported valvular heart disease and primary pulmonary hypertension.
People who have been shown to be healthy before being administered phentermine have developed heart diseases where no other substance could have possibly led to the defect, barring inherent genetic defects.
PPH is a rare, but fatal disease of the lungs. However, just as with cardiovascular diseases, the possibility of phentermine alone leading to PPH cannot be discounted. There have been rare cases of people reporting PPH, having consumed phentermine alone. It is not clearly understood if these people had any underlying genetic issues that could have led to PPH. Dyspnea, which refers to labored or difficult breathing, is typically the initial symptom of PPH. Individuals who experience any breathing difficulties or exercise intolerance as a result of consuming phentermine are advised to consult their physician without any delay.
If other symptoms such as lower extremity edema and angina pectoris show up alongside dyspnea, patients should immediately stop their consumption of phentermine and evaluate themselves for possible signs of primary pulmonary hypertension. Current forms of phentermine Currently one of the most popular variations of phentermine is Qsymia.
Qsymia is a combination of topiramate and phentermine. This is a part of recent efforts to study phentermine in combination with other drugs to increase its effectiveness as a weight loss supplement and reduce its negative side effects.
Qysmia was approved by the FDA for public consumption in For adults who are starting out on Qysmia, the dosage should be no more than phentermine 3. After this initial period, you can normally double our dosage but this general rule does not apply to everyone. Qysmia carries around a lot of the same health risks that characterized earlier forms of phentermine.
It remains to be seen if Qysmia has any similar long-term effects on the body that Fen-Phen and Dexfen-Phen had. As of now, no relationship between Qysmia and mortality or cardiovascular morbidity has been established. People above this BMI are considered to be clinically obese.
Generic Phentermine is one of the medications like this. Brief description of generic Phentermine Generic Phentermine is used as a stimulant. This generic works similarly to an amphetamine. It can be used to treat obesity and overweigh because is an appetite suppressant that affects the central nervous system.
This medication is prescribe when obesity and overweigh lead to major health problems like high blood pressure, diabetes, or high cholesterol. There are also other purposes that generic Phentermine can bu used for.
First generic Phentermine become available on the medication market in as an appetite suppressing drug. Different dosage of drug Phentermine tablets exist, but Phentermine Detailed description of generic Phentermine Drug Phentermine is an appetite suppressant that is used in order to archive weigh loss.
The commonly used dosage of tablets is phentermine 37 5mg. Generic Phentermine is usually used in combination of healthy dieting and exercises. There are contraindications and precaution to using this medication.
Thus, if you combine drug Phentermine with other diet medications like fenfluramine , you may experience fatal lung disorder. Once you have opened the account online, you can request that new prescriptions be filled or refill existing prescriptions after verifying your identity. The consumer can type this information into the online form for the pharmacist.
The pharmacy then starts filling the order and gives the consumer an estimated price. A tentative availability date for pick up will also be provided by your local pharmacy.
You will then be able to go to your local pharmacy on the tentative availability date, usually, the same day, pay for your order, and retrieve your product. You can then click on the prescription by name from your account list and click the refill button.
If you already have available refills on the prescription the order will be processed and a tentative availability date for pick up provided.
If there are no refills left on the prescription, you have the option to contact your doctor or medical professional to request another refill. In which case, the pharmacy will send the request to your doctor.
The doctor will then respond to the pharmacy approving or denying your request for a refill. Please keep in mind, the DEA only allows up to 5 refills of Schedule IV Controlled Substances within a 6 month period before a new prescription will be required to proceed.
Regardless of whether you have initiated a prescription refill order online or submitted a new prescription order online, you must purchase the actual product in person at the pharmacy. Starting the process online only makes the process quicker when you appear at the pharmacy. You will still need to complete the purchase in person at the pharmacy by paying and picking it up at the availability date. Typically, identification will be required at the time of pickup for Schedule IV Controlled Substances.
Although starting a purchase online and having to finish it in person is less than ideal, it may be the safest way to purchase Phentermine online. Nevertheless, many people are eager to use this product to suppress their appetite and start losing weight. So much so that they are unwilling to wait for a proper prescription from a doctor. Some people may even be unable to obtain a prescription from their doctor. Therefore, some people tend to search online for a quicker way to purchase the product completely online.
However, purchasing the product online is not as easy as it may sound. What do I need to know before shopping for Phentermine online? It is important that you are aware of the potential for abuse in searching for the product online.
Although many websites may appear legitimate, and many weight loss supplements may look official, they must be put to the test.
There are many ads for Phentermine on the Worldwide Web. These people will often use an eye-catching website that boasts of the success of their purported Phentermine product. However, the truth is Phentermine cannot be purchased online. A simple internet search for this product online will return several options to purchase the product online. Many of the purchase options even look legitimate.
The paper estimated that in the Fen-Phen combination had been prescribed to nearly 20 million people. Ideally, phentermine should be consumed in the morning an hour or two before the first meal of the day. You will still need to complete the purchase in person at the pharmacy by phentermine and picking it up at the availability date. So much so that they are unwilling to buy for a proper prescription from a doctor. Acute urinary retention is nitroglycerin treatment dysphagia common symptom. Doctors were allowed to prescribe Adipex online the internet without any sort of face-to-face consultation. Therefore, this product is not available for purchase to all consumers. Suprenza is an example of an orally disintegrating form of phentermine, buying phentermine online cheap. The site is cheap selling a product that is not truly Adipex. Since there is a chance to get addicted, generic Phentermine should not be used in longer term than it is prescribed by the doctor and should not be giving to third person.
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