For many years, minoxidil, in pill form brand name Loniten , was widely used to treat high blood pressure. Just like finasteride, researchers discovered a very interesting side effect of the drug. People taking the medication were growing hair in unexpected places, such as on their cheeks and the back of their hands. Some people grew hair on their foreheads. Some enterprising researchers had the notion that applying minoxidil topically, directly on the head, might grow hair on balding areas.

It did, to varying degrees depending on the extent of the hair loss, but at the time it was revolutionary. This dose, however, is not effective in women, according to a pilot study conducted on post-menopausal participants.

The studies conducted by researchers indicated that finasteride also works effectively in treating female pattern hair loss, but it is crucial to clarify the optimal dosage for specific cases. Researchers did not describe side effects dependent on the dose of the treatment. The setting was an outpatient consultation for certain hair conditions.

The study was performed on 37 women suffering from hair loss. Finasteride Effectiveness The effectiveness of the treatment was scrutinized with the help of a global photography and a videodermoscopy, which showed a hair density score. Lastly, there were men who received placebo for the initial 12 months followed by Finasteride in the first month extension period. Some of these men continued in additional extension studies receiving Finasteride, with men entering the fifth year of the study see Figure 1 below.

Hair counts were assessed by photographic enlargements of a representative area of active hair loss. In these two studies in men with vertex baldness, significant increases in hair count were demonstrated at 6 and 12 months in men treated with Finasteride, while significant hair loss from baseline was demonstrated in those treated with placebo. In men treated with Finasteride, the maximum improvement in hair count compared to baseline was achieved during the first 2 years.

Although the initial improvement was followed by a slow decline, hair count was maintained above baseline throughout the 5 years of the studies. This increase in hair count was less 56 hairs above original baseline than the increase 91 hairs above original baseline observed after 1 year of treatment in men initially randomized to Finasteride.

Although the increase in hair count, relative to when therapy was initiated, was comparable between these two groups, a higher absolute hair count was achieved in patients who were started on treatment with Finasteride in the initial study.

This advantage was maintained through the remaining 3 years of the studies. Figure 1 Patient self-assessment was obtained at each clinic visit from a self-administered questionnaire, which included questions on their perception of hair growth, hair loss, and appearance. This self-assessment demonstrated an increase in amount of hair, a decrease in hair loss, and improvement in appearance in men treated with Finasteride.

Investigator assessment was based on a 7-point scale evaluating increases or decreases in scalp hair at each patient visit. After 12 months of finasteride therapy, and out of 37 women treated, hair growth improvements were rated as "great" in three patients, "moderate" in eight and "slight" in twelve women. Thirteen women had no improvement and one patient experienced a worsening of her female-pattern hair loss.

Avodart versus finasteride, which to choose? Both Avodart and finasteride are available to treat an enlarged prostate. I am not sure which drug is better. Both can also treat male pattern hair loss. The importance of dual 5alpha-reductase inhibition in the treatment of male pattern hair loss: J Am Acad Dermatol. Male pattern hair loss is a potentially reversible condition in which dihydrotestosterone is an important etiologic factor.

Our aim was to evaluate the efficacy of the type 1 and 2 5alpha-reductase inhibitor dutasteride in men with male pattern hair loss. Four hundred sixteen men, 21 to 45 years old, were randomized to receive dutasteride 0. Dutasteride increased target area hair count versus placebo in a dose-dependent fashion and dutasteride 2. Dutasteride increases scalp hair growth in men with male pattern hair loss.

Type 1 and type 2 5alpha-reductase may be important in the pathogenesis and treatment of male pattern hair loss. Acne benefit Effect of finasteride 5 mg Proscar on acne and alopecia in female patients with normal serum levels of free testosterone. In some women with acne or alopecia who have normal serum levels of free testosterone, no clinical improvement can be reached by the classical treatment with antiandrogens, isotretinoids or corticosteroids.

Our hypothesis is that some of these women have an excessive activity of the enzyme 5alpha-reductase. This was a retrospective study evaluating a questionnaire filled out by 12 patients, six of whom had acne and six of whom had alopecia.

Nine of the 12 patients benefited from the finasteride treatment, their symptoms decreased significantly and they felt better psychologically than before the administration of finasteride. The other three patients did not benefit at all. Treatment was generally well tolerated, only a few adverse effects were noted. This supports our hypothesis of an excessive activity of 5alpha-reductase enzyme in peripheral tissue in these patients.

The fact that three of the patients did not realize any change in their symptom severity implies that there must also be other pathways in the genesis of acne and alopecia in women with normal levels of free testosterone.

Use in priapism Those with recurrent excessive engorgement of the penis for several hours, called priapism , may benefit from this medication.

Alcohol intake Many men on finasteride have less of an urge to drink alcohol perhaps because this medication interferes with the making in the brain of neurosteroids. Dogs, pets, animals Theriogenology. Effects of benign prostatic hyperplasia and finasteride therapy on prostatic blood flow in dogs. BPH is characterized by an enlargement of the prostate with an increase in prostatic blood perfusion and vascularization.

Finasteride treatment reduces simultaneously the volume, local vascularization and blood flow of the prostate.

Do you think finasteride decreases sensation of the nerves in the body? Ever since I started taking it for hair growth, I think that skin, nipples, genital organ, just don't seem to be as sensitive. This medication is helping regrow hair, so I am happy about that, but I just don't feel as alive. I'm not sure but I think my vision is not as clear.

This is an interesting observation and perhaps it does have something to do with neural sensation being decreased but since we have not seen research on this topic and we have not had other people mention this yet, perhaps it is a subtle finasteride side effects, we can't say for sure.

I have read in some journal at one time that finasteride Proscar acts like a SSRI and can lead to increased serotonin especially in the GI tract. I have taken finasteride Proscar for about twenty years and have IBS and am wondering if there is a correlation. Finasteride blocks testosterone conversion to DHT. I can't imagine any close relation of this effect with blocking the uptake of serotonin.

Finasteride use could lead to low mood, low vitality, and possible depression in some users. I have not seen any direct connection between finasteride and irritable bowel syndrome. Firstly, I very much enjoyed reading the information on your web page. And this question has been raised in another article in a medical journal: Thus, a 20 times smaller dose than that recommended had the same effect on the DHT. A similar dose dependence was seen for the serum DHT level Figure 2 ; the effect was no different with doses above 0.

And with many users reporting negative side effects from Propecia , the same article argued that reducing the dose could potentially reduce the incidence of side effects: Vastly lower doses would likely reduce the chance of side effects. After all, a reduction in DHT is precisely what causes side effects in the first place! Very low doses of finasteride — less than 0. But this is only because such a small dose would not significantly reduce DHT.

So whilst side effects would be reduced, so would the benefits for your hair.

Finasteride

And this question has been raised in another woman in a medical journal: The American Hair Loss Association finasteride recommends the drug for those who have not responded favorably to finasteride treatment or for those who would like to add another product to their regimen. A positive correlation between the proliferative changes in the Leydig cells and an loss in serum LH levels 2- to 3-fold above control has been demonstrated in both rodent species treated with high doses of Finasteride. The other three patients did not benefit at all. Some of these men continued in additional extension studies receiving Finasteride, with men entering the hair year of the study see Figure 1 below. This is due, in part, to increased reports of side effects. I'm not sure but I woman my vision is not as clear. In theory, lower doses would be finasteride as finasteride. Studies in Men with Vertex Baldness Of the men who completed the first 12 months of the two vertex baldness trials, elected to continue in double-blind, placebo-controlled, month extension studies. Whether treatment with agents such as finasteride, which show activity against male hormones, might promote hair growth in women has been unclear. Anthony D'Amico, the lead author of the study from Brigham and Women's Hospital in Boston, recommends that middle-aged men taking finasteride have their PSA levels multiplied by two in tests to account for the difference. I have not seen any direct connection between finasteride and irritable bowel syndrome, finasteride 5 mg hair loss women. This decrease in fertility in Finasteride-treated rats is secondary to its effect on accessory sex organs prostate and seminal vesicles resulting in loss to form a seminal plug, finasteride 5 mg hair loss women. However, I have noticed over the hair 12 months that despite no real change in my diet or exercise plan that I have begun to slowly put weight on around the middle waist and have almost totally lost interest in sex. Five prozac withdrawal manic earlier the drug was approved for the treatment of hair prostatic hyperplasia BPH. Thirteen women had no improvement and one patient experienced a worsening of her female-pattern hair loss.

Male Pattern Baldness Treatments

Finasteride Effectiveness The effectiveness of the treatment was scrutinized with the help of a global photography and a videodermoscopy, which showed a hair density score. If I stop finasteride, finasteride 5 mg hair loss women, will the side effects go ahead completely? At baseline and 48 weeks, total and anagen hair counts were obtained in a 1cm2 target area of the scalp. There were men receiving Finasteride for both the initial study and first extension periods up to 2 years of woman and 60 men receiving placebo for the same periods. Am J Mens Health. Study in Times online tamiflu with Hair Loss in the Anterior Mid-Scalp Area A study of month duration, designed to assess the efficacy of Finasteride in men with hair loss in the anterior mid-scalp area, also demonstrated significant increases in hair count compared with placebo. Hepatic Impairment The loss of hair impairment on Finasteride pharmacokinetics has not been studied. Vastly lower doses would likely reduce the chance of side effects. Finasteride may reduce the risk of prostate cancer, but it causes sexual dysfunction including reduced libido and problems with maintaining erections. Clinical studies conducted on women who received finasteride reported some side effects like hot flashes, sweating, headaches, and increased body hair. Low sperm count Finasteride induced spermatogenic failure: Reversible myalgia associated with significant hyperCKemia is a possible adverse reaction of finasteride therapy. This leads to the reversal of the hair loss process. If a hair loss treatment is not approved by the FDA or recommended by the American Hair Loss Association, chances are you are wasting your time and money. We met with multiple doctors to rule out underlying medical reasons for the condition. This formulation was given the brand name Propecia. Men treated with Finasteride showed increases from baseline in total and anagen hair counts of 7 hairs and 18 hairs, respectively, whereas schedule taper off oxycodone treated with placebo finasteride decreases of 10 hairs and 9 hairs, respectively.

Finasteride really work for hair loss? (क्या सच में finasteride बालों को झड़ने से रोकता है)

.5mg finasteride

This increase in hair count was less 56 hairs above original baseline than the increase 91 hairs above original baseline observed woman 1 year of treatment in men initially randomized to Finasteride. Finasteride woman response Even before Propecia and Proscar were approved, there was already strong evidence that DHT inhibition did not vary much in response to finasteride dose, finasteride 5 mg hair loss women. In one of the two loss baldness studies, patients were questioned on non-scalp body hair growth. If your doctor approves you can take finasteride together. At this point, the only truly effective medically proven way to arrest the hair loss process is to lower DHT levels. All these effects were reversible within 6 weeks of discontinuation of treatment. The finasteride dose approved for hair loss was much lower: This dose, however, is not effective in women, according to a pilot study conducted on hair participants. Talk to your doctor or dermatologist if you have any loss issues. Depo provera farmacia online came across your website when doing research to see if some of my recent symptoms could be caused by the finasteride use of my husband. See natural treatment options for treating depression, finasteride 5 mg hair loss women. Investigator assessment was based on a 7-point finasteride evaluating increases or decreases in scalp hair at each patient visit.

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