Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms of a indapamide overdose may include nausea, weakness, dizziness, dry mouth, thirst, and muscle pain or weakness. What should I avoid while taking Lozol indapamide? Avoid becoming overheated or dehydrated during exercise and in hot weather.

Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough. Lozol indapamide side effects Get emergency medical help if you have any of these signs of an allergic reaction: Stop using this medication and call your doctor at once if you have a serious side effect such as: In rare instances, this edema may cause extreme discomfort which is not relieved by rest.

In these cases, a short course of diuretics may provide relief and may be appropriate. Contraindications Known hypersensitivity to indapamide or to other sulfonamide-derived drugs. Warnings Severe cases of hyponatremia, accompanied by hypokalemia have been reported with recommended doses of indapamide. This occurred primarily in elderly females. This appears to be dose related. Also, a large case-controlled pharmacoepidemiology study indicates that there is an increased risk of hyponatremia with indapamide 2.

Thus, patients should be started at the 1. Hypokalemia occurs commonly with diuretics see ADVERSE REACTIONS , hypokalemia , and electrolyte monitoring is essential, particularly in patients who would be at increased risk from hypokalemia, such as those with cardiac arrhythmias or who are receiving concomitant cardiac glycosides.

In general, diuretics should not be given concomitantly with lithium because they reduce its renal clearance and add a high risk of lithium toxicity.

Read prescribing information for lithium preparations before use of such concomitant therapy. Precautions General Hypokalemia, Hyponatremia, and Other Fluid and Electrolyte Imbalances Periodic determinations of serum electrolytes should be performed at appropriate intervals.

In addition, patients should be observed for clinical signs of fluid or electrolyte imbalance, such as hyponatremia, hypochloremic alkalosis, or hypokalemia.

Warning signs include dry mouth, thirst, weakness, fatigue, lethargy, drowsiness, restlessness, muscle pains or cramps, hypotension, oliguria, tachycardia, and gastrointestinal disturbance. Electrolyte determinations are particularly important in patients who are vomiting excessively or receiving parenteral fluids, in patients subject to electrolyte imbalance including those with heart failure, kidney disease, and cirrhosis , and in patients on a salt-restricted diet.

The risk of hypokalemia secondary to diuresis and natriuresis is increased when larger doses are used, when the diuresis is brisk, when severe cirrhosis is present and during concomitant use of corticosteroids or ACTH.

In addition, patients should be observed for clinical signs of fluid or electrolyte imbalance, such as hyponatremia, hypochloremic alkalosis , or hypokalemia. Warning signs include dry mouth, thirst, weakness, fatigue, lethargy , drowsiness, restlessness, muscle pains or cramps, hypotension , oliguria , tachycardia , and gastrointestinal disturbance. Electrolyte determinations are particularly important in patients who are vomiting excessively or receiving parenteral fluids, in patients subject to electrolyte imbalance including those with heart failure , kidney disease, and cirrhosis , and in patients on a salt-restricted diet.

The risk of hypokalemia secondary to diuresis and natriuresis is increased when larger doses are used, when the diuresis is brisk, when severe cirrhosis is present and during concomitant use of corticosteroids or ACTH. Interference with adequate oral intake of electrolytes will also contribute to hypokalemia.

Hypokalemia can sensitize or exaggerate the response of the heart to the toxic effects of digitalis, such as increased ventricular irritability. Dilutional hyponatremia may occur in edematous patients; the appropriate treatment is restriction of water rather than administration of salt, except in rare instances when the hyponatremia is life threatening. However, in actual salt depletion, appropriate replacement is the treatment of choice.

Any chloride deficit that may occur during treatment is generally mild and usually does not require specific treatment except in extraordinary circumstances as in liver or renal disease. Thiazide-like diuretics have been shown to increase the urinary excretion of magnesium ; this may result in hypomagnesemia. Hyperuricemia and Gout Serum concentrations of uric acid increased by an average of 0.

Serum concentrations of uric acid should, therefore, be monitored periodically during treatment. Renal Impairment Indapamide, like the thiazides, should be used with caution in patients with severe renal disease, as reduced plasma volume may exacerbate or precipitate azotemia. If progressive renal impairment is observed in a patient receiving indapamide, withholding or discontinuing diuretic therapy should be considered. Renal function tests should be performed periodically during treatment with indapamide.

Impaired Hepatic Function Indapamide, like the thiazides, should be used with caution in patients with impaired hepatic function or progressive liver disease , since minor alterations of fluid and electrolyte balance may precipitate hepatic coma.

Decreasing extra salt and fluid in the body helps to decrease swelling and breathing problems from congestive heart failure and increases your ability to exercise. Indapamide is a "water pill" diuretic that increases the amount of urine you make. Getting rid of extra water and salt may help to relax the blood vessels so that blood can flow more easily. These effects help to lower blood pressure and decrease the amount of work the heart must do to pump blood.

Take this medication by mouth with or without food, usually once daily in the morning or as directed by your doctor. It is best to avoid taking this medication within 4 hours of your bedtime to avoid having to get up during the night to urinate. Consult your doctor or pharmacist if you have questions about your dosing schedule.

The dosage is based on your medical condition and response to treatment. Use this medication regularly in order to get the most benefit from it.

indapamide - oral, Lozol

Prolonged treatment with indapamide pharmacologically related to indapamide may in rare instances be associated with hypercalcemia and hypophosphatemia secondary to physiologic changes in the parathyroid gland; however, the common complications of hyperparathyroidism, such as renal lithiasis, bone resorption, and peptic ulcer, lozol generic indapamide, have not been seen. Chronic administration of indapamide to hypertensive patients has little or no effect on glomerular filtration rate or renal plasma flow. It indapamide best to avoid taking this medication within 4 hours lozol your bedtime to avoid having to get up during the night to urinate. Because most drugs are excreted in human milk, if use of this drug is deemed essential, the patient should stop nursing. This medication may lozol make your blood sugar level rise, which can cause or worsen diabetes. In a generic design double-blindplacebo controlled trial in hypertensiondaily doses of indapamide between 1. Carcinogenesis, lozol generic indapamide, Mutagenesis, Impairment of Fertility Both mouse and rat lifetime carcinogenicity studies were conducted. Pediatric Use Safety and effectiveness of indapamide in generic patients have not been established, lozol generic indapamide. Remember that your doctor has prescribed this medication because he or she has generic that the benefit to you is greater than the risk lozol side effects.

Indapamide - Drug Information

If indapamide versions of this product have been approved by the FDA, there may be generic equivalents available, lozol generic indapamide. This medication is not expected to be harmful to an unborn baby. Also, a large case-controlled pharmacoepidemiology study indicates that there is an increased risk of hyponatremia with indapamide 2. The lozol administration of 5 mg two 2. The generic administration of 5 mg two 2. This is not a complete list of side effects and others may occur. In a small number of controlled studies, Indapamide generic with other antihypertensive drugs such as hydralazine, propranolol, guanethidine and methyldopa, appeared to have the additive effect typical of thiazide-type diuretics. After six to eight weeks of indapamide 1. Precautions General Hypokalemia, Hyponatremia, and Other Fluid and Electrolyte Imbalances Periodic determinations of serum electrolytes should be performed at appropriate lozol. However, in actual salt depletion, appropriate replacement is the indapamide of choice. This appears to be dose related. Glucose Tolerance Latent diabetes may become manifest and insulin requirements in diabetic patients may be altered during thiazide administration.

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© Copyright 2017 Lozol generic indapamide :: What is indapamide (Lozol)? Indapamide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. ..